Immunity in responses to nanoparticles

Abstract

Nanotechnology is widely used for current industry, health sciences and medicine in the different utilization such as drug delivery materials, safe vaccines, cosmetics, material replacement organs or tissue, biosensors. Human may have chance to expose to nanoparticles directly or in directly.  The understanding of immune system in response to nanoparticles is important. The mechanisms of the immune responses are related to the characteristics of nanoparticles such as sizes, shapes, surface charges, and molecular connectivity on nanoparticles. Interestingly, these properties can be conducted on to the immune responses in both immunostimulation and immunosuppression. This review article focuses on the functions and effects of the immune system in responses to nanoparticles. Therefore, this knowledge gives advantage for the development of nanoparticles for application in health, as well as in devices used in everyday life, in order to promote a better quality of life.