Abnormal Papaniculaou Smear in HIV Infected Women In Pathumthani Hospital
Keywords:
Papaniculaou smear, infected womenAbstract
The purpose of this study was to compare the incidence of abnormal Papaniculaou smear in human immunodeficiency virus infected women and non infected women in Pathumthani hospital and their association with Papaniculaou smear, demographic characteristics and para history. Records of 77 women were reviewed. Studied group comprised 29 women with HIV-infected and controlled group comprised 58 non HIV-infected women. Demographic characteristics, para history and smear results were examined. Student t-test, Chi square test and Fisher exact test analysis were used for analysis of data. Studied group had abnormal Papaniculaou smear more than controlled group with statistical significance (p<0.001). Cases were more significant than controls to have lower age, lower para, higher vaginal infection (p<0.001, p=0.03, p=0.04 respectively). In conclusion, HIV infected women should routinely received Papaniculaou smear to early detected abnormal results.
References
2. ภูชิชย์ มีประเสริฐสกุล. ความผิดปกติของการตรวจมะเร็งปากมดลูกในสตรีที่ติดเชื้อเอดส์ในสถาบันบำราศนราดูร. วารสารโรคติดต่อ 2547; 30(4): 337-43.
3. National Institute for Clinical Excellence. Final appraisal consultation document: guidance on the use of liquid-based cytology for cervical screening (review of existing guidance Number 5) (monograph on line). London: NICE, 2003.
Available online at http://www.nice.org.uk/Docref.asp?d=82877.
4. Centers for Disease Control. Risk for cervical disease in HIV-infected women, New York City. MMWR 1990; 864-9.
5. Vermund SH, Kelly KF, Klein RS, et al. High risk of human papilloma virus infection and cervical intraepithelial lesion among women with symptomatic human immunodeficiency virus infection. Am J Obstet Gynecol 1991; 165: 392-400.
6. Saslow D, Runowicz CD, Solomon D, Moscicki A, Smith RA, Eyre HJ, et al. American Cancer Society guideline for the early detection of cervical neoplasia and cancer. CA Cancer J Clin 2002; 52: 342-62.
7. Davey E, Barratt A, Irwig L, Chan SF, Makaskill P, Mannes P, et al. Effect of study design and quality on unsatisfactory rates, cytology classification, and accuracy rate in liquid- based cytology versus conventional cervical
cytology: a systematic review. Lancet 2006; 367: 122-32.
8. Walboomers JM, Jacobs MV, Manos MM, Bosch FX, Kummer JA, Shah KV, et al. Human papilloma virus is a necessary cause of invasive cervical cancer worldwild. J Pathol 1999; 189: 12-9.
9. Smith Jr, Kitchen VS, Bothcherby M, et al. Is HIV infection associated with an increase in the prevalence of cervical neoplasia? Br J Obstet Gynaecol 1993; 100:149-53.
10. Maiman M, Fruchter RG, Serur E, Levine PL, arrastia C, Sadlis A. Recurrent cervical intraepithelial neoplasia in human immunodeficiency virus-seropositive women. Obstet Gynecol 1993; 82: 170-4.
11. อัจฉรา เชาววฌิช, อมรพันธุ์ วิรัชชัย, วรวิทย์ วิศิษฎกิจการ และคณะ. ความผิดปกติของ Papaniculaou smear ในสตรีติดเชื้อเอดส์ในโรงพยาบาลบำราศนราดูร. วารสารโรคติดต่อ 2539; 22(2): 159-68.
12. Marte C, Kelly P, Cohen M, et al. Papanicolaou smear abnormalities in ambulatory care sites for women infected with the human immunodeficiency virus. Am j Obstet Gynecol 1992; 166: 1232-7.
13. Fruchter RG, Maiman M, Sillman FH, Camilien L, Webber CA, Kim DS. Characteristics of cervical intraepithelial neoplasia in women infected with the human immunodeficiency virus. Am J Obstet Gynecol 1994; 171: 531-7.
14. Maiman M, Tarricone N, Viera J, et al. Colposcopic evaluation of human immunodeficiency virus seropositive women. Obstet Gynecol 1991; 78: 84-8.
15. Fink MJ, Fruchter RG, Maiman M, Webber CA, Chen P, Kelly P. Cytology, colposcopy and histology in HIV positive women. [Abstract POB23-1947]. In: Proceedings of the ninth annual international conference on AIDS, 1993:
460.
16. Heard I, Tassie JM, Schmitz V, et al. Increased risk of cervical disease among human immunodeficiency virus-infected women with severe immunosuppression and high human papillomavirus load. Obstet Gynecol. 2000; 96: 403-9.
17. Maiman M, Fruchter RG, Sedlis A, et al. Prevalence, risks factors, and accuracy of cytologic screening of cervical intraepithelial neoplasia in women with immunodeficiency virus. Gynecol Oncol 1998; 68: 233-9.
18. Petry KU, Bohmer G, Iftner T, et al. Human papillomavirus testing in primary screening for cervical cancer of human immunodeficiency virus-infected women, 1990-1998. Gynecol Oncol 1999; 75: 427-31.
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