Factors associated with tuberculosis treatment outcomes among patients aged ≥60 years

  • วิลาวรรณ สมทรง Bureau of Tubercuosis, Department of Disease Control
Keywords: tuberculosis treatment outcomes, patients aged ≥60 years

Abstract

Tuberculosis (TB) is emerging as a significant health problem among the elderly. Patients with pulmonary tuberculosis (PTB) of advanced age were less likely to achieve treatment success and the proportion of death showed a substantial increase with age. This study aimed to determine the association between factors and treatment outcomes among patients aged ≥60 years. A retrospective cohort study was conducted. A total of 8,359 elderly PTB patient records were extracted from the TBCM databases (TB Case Management) of the Bureau of Tuberculosis, Department of Disease Control. The study group comprised all new smear-positive PTB patients aged 60 years and above registered for treatment between 1 October 2015 and 30 September 2016. The overall treatment success rates were 77.60% and mortality rate were 16% among PTB patients aged ≥60 years. Patient’s age, sex, and HIV status were associated with treatment success among patients aged ≥60 years with PTB. The high treatment success rates were shown among patients aged 60 to 69 years (83.60%), among female elderly PTB patients (80.30%), and among elderly PTB patients with HIV negative (79.80%). Patient’s age, sex, grading of AFB, and HIV status were associated with death during TB treatment among PTB patients aged 60 years and above. The high mortality rates were reported among patients aged ≥80 years (33.80%), among male elderly PTB patients (16.80%), among PTB patients had smear 3+ positive results (17.40%), and among elderly PTB patients had positive anti-HIV test results (33.30%). Elderly TB patients undergoing treatment with anti-TB drugs should be closely monitored and should complete TB treatment course as these will result in an increased TB treatment success rate.

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Published
2019-06-28
Section
Original Article