Cardiac metastasis of acute lymphoblastic leukemia among adult patients
Keywords:
cardiac involvement, acute lymphoblastic leukemiaAbstract
Cardiac metastasis is an uncommon clinical complication of acute lymphoblastic leukemia (ALL). We
reported two new cases of T-cell and B-cell ALL who presented with different clinical manifestations of cardiac
leukemia at the time of initial diagnosis. We also demonstrated the advantage of echocardiography and computed
tomography scan in the diagnosis and follow-up of patients. The cardiac involvements improved after the
treatment of acute leukemia by chemotherapy and radiotherapy.
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References
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2. Roberts WC, Bodey GP, Wertlake PT. The heart in acute leukemia. A study of 420 autopsy cases. Am J Cardiol. 1968;21:388-412.
3. Barbaric D, Holley D, Lau K-C, McCowage G. It is ALL in the heart: a patient with acute lymphoblastic leukemia and cardiac infiltration at time of diagnosis. Leuk Lymphoma. 2002;43:2417-9.
4. Wright TL, Bardy PG, Disney P, Moore S, Horvath N. Isolated cardiac recurrence of acute lymphoblastic leukemia characterized by t(11;19) two years after unrelated allogeneic bone marrow transplantation. Cancer Genet Cytogenet. 2002;137:146-9.
5. Hori T, Suzuki N, Mizue N, Hatakeyama N, Takamuro M, Tsutsumi H. Relapse of T-cell all after stem cell transplant presenting as hypertrophic cardiomyopathy: the value of non-invasive diagnostic imaging in detecting cardiac leukemia. Pediatr Blood Cancer. 2006;46:108-11.
6. Hardikar A, Shekar P, Stubberfield J, Craddock DR, Bignold LP. Cardiac involvement in a case of acute lymphoblastic leukemia. Ann Thorac Surg. 2002;73:1310-2.
7. Kahwash R, Rugg SS, Smith MD. Relapsing B-cell lymphoblastic leukemia in an adult presenting as an infiltrative cardiac mass with tamponade. J Am Soc Echocardiogr. 2007;20:1319.e1-2.
8. Kara IO, Sahin B, Paydas S, Kara B. Granulocytic sarcoma of the heart: extramedullary relapse of acute myeloblastic leukemia after allogeneic stem cell transplantation successfully treated by chemotherapy alone. Leuk Lymphoma. 2005;46:1081-4.
9. Rigamonti F, Beris P, Sanchez-Pareja A, Meyer P, Ashrafpoor G, Zaza S, et al. Atypical presentation of acute myeloid leukemia: cardiac myeloid sarcoma. Int J Hematol. 2009;89:693-8.
10. Kozelj M, Zorman D, Mrevlje B, Cernelc P, Zver S. Cardiac granulocytic sarcoma diagnosed by intracardiac echocardiographyguided biopsy. Int J Hematol. 2008;88:101-3.
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Published
2019-12-23
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รายงานผู้ป่วย (Case report)
