Endogenous Endophthalmitis : Report of a 10-year Retrospective Study at Buriram Hospital

Main Article Content

Thanit Sirilekanunt


Objective: To study clinical features, risk factor and visual outcomes in patients with endogenous endophthalmitis at Buriram hospital
Design: Retrospectivedescriptive study
Methods: Review of medical records of 16 patients with endogenous endophthalmitis, who has medical record between January 2006 – December 2015 at Buriam hospital.
Results: 17 eyes of 16 patients were diagnosed with endogenous endophthalmitis. Patient with underlying disease are 13 from 16 patients. Most common risk factor was diabetes mellitus (54%). Causative organismfrom vitreous were identified 42%of patients. The most common organism in bacterial group were Streptococcus spp.(12%) and klebsella spp.(12%) Source of infection was frequent in arthritis (13%). 11 eyes (65%) obtained no light perception and 6 eyes (35%) with visual acuity less than 20/200. Final visual outcome were poor even with broad spectrum antibiotic treatment. Only 1 eye in this study receive better visual acuity after treatment.
Conclusion: Endogenous endophthalmitis is rare but cause severe visual loss. Prompt diagnosis and intensive intravenous antibiotic are the critical steps in the treatment of endogenous endophthalmitis. The Patients who have severe systemic infection and risk factors such as diabetes should have ocular screening.
Keyword: endogenous endophthalmitis, septicemia, ophthalmology,Buriram,Thailand.


Article Details

Original Articles


1. Shrader SK, Band JD, et al. The clinical spectrum of endophthalmitis: incidence, predisposing factors, and features influencing outcome. J Infect Dis. 1990 Jul;162(1):115-20.

2. Binder MI, Chua J, et al. Endogenous endophthalmitis: an 18-year review of culture-positive cases at a tertiary care center. Medicine (Baltimore). 2003 Mar;82(2):97-105.

3. Wong JS, Chan TK, et al. Endogenous bacterial endophthalmitis: an east Asian experience and a reappraisal of a severe ocular affliction. Ophthalmology. 2000 Aug;107(8):1483-91.

4. Sheu SJ, Kung YH, et al. Risk factors for endogenous endophthalmitis secondary to klebsiella pneumoniae liver abscess: 20-year experience in Southern Taiwan. Retina. 2011 Nov;31(10):2026-31.

5. Okada AA, Johnson RP, et al. Endogenous bacterial endophthalmitis. Report of a ten-year retrospective study. Ophthalmology. 1994 May;101(5):832-8.

6. Greenwald MJ, Wohl LG, Sell CH. Metastatic bacterial endophthalmitis: a contemporary reappraisal. SurvOphthalmol. 1986 Sep-Oct;31(2):81-101.

7. Menezes AV, Sigesmund DA, et al. Mortality of hospitalized patients with Candida endophthalmitis. Arch Intern Med. 1994 Sep 26;154(18):2093-7.

8. Mowat A, Baum J. Chemotaxis of polymorphonuclear leukocytes from patients with diabetes mellitus. N Engl J Med. 1971 Mar 25;284(12):621-7.

9. Yoon YH, Lee SU, et al. Result of early vitrectomy for endogenous Klebsiella pneumoniae endophthalmitis. Retina. 2003 Jun;23(3):366-70.