Laparoscopic Radical Prostatectomy: Initial Experience in Srinagarind Hospital

Main Article Content

Wichien Sirithanaphol Ukrit Rompsaithong Pakorn Kiatsopit Supanut Lumbiganon Kachit Pachirat

Abstract

Background and objective: The standard treatment for clinically localized prostate cancer is surgery, radical prostatectomy. With the gaining acceptance of minimally invasive surgery, laparoscopic radical prostatectomy (LRP) has been determined to be an effective procedure in an experienced surgeon's hands. This study reported initial experience of LRP in Srinagarind hospital.


Methods:  Medical records of 20 patients with clinically localized prostate cancer who underwent LRP by a single urologist in Srinagarind hospital between October 2016 to February 2019 were retrospectively reviewed. Patient characteristics, operative and peri-operative details, post-operative complications, and oncological outcomes were assessed.


Results: The median age was 67.5 years (57-76). The mean pre-operative prostate specific antigen level was 14.1 ng/mL (6-39). Seven patients were treated with GnRH agonist before the operation. The median operative time and blood loss were 180 min (120-330) and 400 ml (100-2000), respectively. Only one operation had to be converted  to open surgery as a result of hemodynamic instability. The median hospital stay was 5 days and no one had to be readmitted. Fourteen patients (70%) were margin negative in the pathological specimen.


Conclusion: From this preliminary study, LRP is safe and feasible, with acceptable oncological outcomes for early prostate cancer in Srinagarind hospital.

Keywords

Article Details

Section
Original Articles

References

1. Khuhaprema T. Current cancer situation in Thailand. Thai J Toxicology 2008;23:69-1.
2. Schuessler WW, Schulam PG, Clayman RV, Kavoussi LR. Laparoscopic radical prostatectomy: initial short-term experience. Urology. 1997; 50: 854–7.
3. Walsh P, Partin A, Epstein. Cancer control and quality of life following anatomical radical retropubic prostatectomy: results at 10 years. J Urol 1994; 152: 1831–6.
4. Zincke H, Oesterling J, Blute M, Bergstralh E, Myers R, Barret D. Long term (15years) results after radical prostatectomy for clinically localized (stage T2c or lower) prostate cancer. J Urol 1994; 152: 1850–7.
5. Trabulsi EJ, Guillonneau B. Laparoscopic radical prostatectomy. J Urol 2005; 173: 1072.
6. Guillonneau B, Vallancien G. Laparoscopic radical prostatectomy: initial experience and preliminary assessment after 65 operations. Prostate. 1999; 39: 71-5.
7. Abbou CC, Salomon L, Hoznek A, Antiphon P, Cicco A, Saint F, et al. Laparoscopic radical prostatectomy: preliminary results. Urology 2000; 55: 630-4.
8. Turk I, Deger S, Winkelmann B, Schonberger B, Loening SA. Laparoscopic radical prostatectomy. Technical aspects and experience with 125 cases. Eur Urol 2001; 40: 46-52; discussion 3.
9. Bollens R, Vanden Bossche M, Roumeguere T, Damoun A, Ekane S, Hoffmann P, et al. Extraperitoneal laparoscopic radical prostatectomy. Results after 50 cases. Eur Urol 2001; 40: 65-9.
10. Nualyong C, Srinualnad S, Taweemonkongsap T, Amornvesukit T. Laparoscopic radical prostatectomy: preliminary result of Thailand series. J Med Assoc Thai 2006; 89: 1440-6.
11. Ramart P, Leewansangtong S, Amornvesukit T, Taweemongkongsap T, Nualyong C, Sujijantararat P. Laparoscopic radical prostatectomy, Siriraj resident experiences: the first resident series in Thailand. J Med Assoc Thai 2011; 94: 50-4.
12. Rassweiler J, Sentker L, Seemann O, Hatzinger M, Rumpelt HJ. Laparoscopic radical prostatectomy with the Heilbronn technique: an analysis of the first 180 cases. J Urol 2001; 166: 2101-8.