Assessment of Central Arterial Stiffness in Healthy Thais by Non-invasive Technique

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Kiattisak Chaiprom Weerapon Sangartit Orapin Pasurivong Veerapol Kukongviriyapan Watchara Boonsawat Arunrat Srithawong Jirawat Wattanapanyawech Upa Kukongviriyapan

Abstract

Background and Objective: Central arterial stiffness is an independent predictor of cardiovascular morbidity and mortality. Carotid-femoral pulse wave velocity (cfPWV) is regarded as the gold standard marker of central arterial stiffening. However, there is limited information available on the values of cfPWV in Thai population. Therefore, the current study aimed to measure the normal values of cfPWV in healthy Thais.


Methods: A total of 163 identified healthy subjects (82 female, 81 male), aged 20-60 years were recruited in this study. The subjects were divided into 4 age groups with 10-year intervals. Blood pressures of peripheral and central arteries and cfPWV were measured non-invasively by using the applanation tonometry.


Results: The systolic blood pressure and pulse pressure of central artery increased progressively with age. The mean values of cfPWV in men and women were increased with age. Moreover, cfPWV was correlated with age and central blood pressure. 


Conclusion: The present study provides normal values of cfPWV in healthy, normotensive and non-metabolic disorder subjects. A pronounced increase in cfPWV was demonstrated in healthy Thais aged over 50 years.  

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References

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