The Outcome of Glomerular Disease Treatment after Kidney Biopsy at Roi Et Hospital, Roi Et Province, Thailand

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Surachat Jaroonpipatkul Narongchai Sangsa Nuntiput Putthanachote


Background and Objective: Chronic kidney disease is a major public health problem in Thailand and trend to be increasing every year. Patients with chronic kidney disease have to pay a big amount of budget for treatment each year. The objective of this study was to study the effectiveness of treatment of patients with glomerular disease by considered kidney biopsy pathology reported, patients clinical, and laboratory blood and urine examination reports. 

Methods: This study were collected data from medical records of 38 patients with glomerular disease and got kidney biopsy and treatment at Roi Et hospital during January 1, 2015 to December 31, 2018 and considered for kidney biopsy pathology reported, patients clinical, and laboratory blood and urine examination reports.  Statistical analyses were used descriptive statistics and paired t-test.

Results: Of 38 cases most of them were male 68.31 %, mean age 38. 37±15.54, body mass index between 18.5-22.9 kg/m2 (50.00%), diabetes mellitus 42.11%,  and hypertension 20.15%. Most of  pathological reported were Lupus nephritis class IV 18.42%, and Immunoglobulin A nephropathy18.42%.  After 6 months of  surgery follow up the results showed that the found Creatinine mean was 1.11± 2.47 mg/dl, Estimated glomerular filtration rate (eGFR) mean was 74.59±42.18,  Albumin mean was 3.66±0.75 mg/dl, Cholesterols mean was 203.13±75.67 mg/dl and Urine protein to creatinine ratio (UPCR) mean was 1.20±1.97g/gCr. The comparison of blood chemical tests between before and after 6 months surgery cholesterols level was found decreased significantly (p <0.001).

Conclusion: Overall patients with glomerular disease after treatment were clinical getting better and after 6 months of surgery cholesterols level was significantly decreases.


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