Quality of life and kidney function of living kidney donors at the Faculty of Medicine, Chiang Mai University

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Danai Kaewjongprasit Jakkrit Jun-U Akara Amantakul Siwat Phuriyaphan


Objective: To compare the quality of life, residual kidney function, and complications of kidney donors before and after donation at the Faculty of Medicine, Chiang Mai University, Thailand.

Material and method: This prospective cohort study included 76 participants who visited the clinic for planning donor nephrectomy and/or routine follow-up after donation between November 2015 and June 2017. The primary outcome was the quality of life of living kidney donors after donation at the short-term and long-term follow-ups, assessed using the SF-36 questionnaire. The secondary outcome was the assessment of residual kidney function after donation. Other potential consequences of kidney donation are also reported in our study, including hypertension, proteinuria, complications during pregnancy, and second thoughts.

Result: Quality of life showed a decline in the early post-donation period but gradually improved over time, especially as regards physical components. The overall quality of life in kidney donors remained higher than in the general population after donation. Sixty-three donors had a GFR >60 mL/min/1.73 m2 after donation. Eight donors had a GFR of 45-59 mL/min/1.73 m2. Five donors did not visit the clinic for routine follow-up after donation due to transportation difficulties. No significant proteinuria was detected in our study. Two donors developed hypertension after donation. Two donors became pregnant after donation and underwent successful delivery without complication. One donor regretted her decision because of an early graft loss in her recipient due to renal vein thrombosis.

Conclusion: Donor nephrectomy is recognized as a safe procedure. A decrease in quality of life after donation was observed only in the early post-donation period. Mental health was not affected by kidney donation. Overall quality of life in kidney donors was higher than in a comparative general population. Residual kidney function after donation was at an acceptable level based on GFR.



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Kaewjongprasit, D., Jun-U, J., Amantakul, A., & Phuriyaphan, S. (2018). Quality of life and kidney function of living kidney donors at the Faculty of Medicine, Chiang Mai University. The Thai Journal of Urology, 39(1), 26-35. Retrieved from https://www.tci-thaijo.org/index.php/TJU/article/view/125732
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