Epilepsy and Neurodevelopmental Disorders: A Biological Perspective Epilepsy And Neurodevelopmental Disorder
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Abstract
Childhood epilepsy represents a complex group of seizure disorders with neuropsychological Childhood epilepsy represents a complex group of seizure disorders with neuropsychological deficits and diverse outcomes during developmental stages and later in life. Epilepsy can lead to neurodevelopmental disorders, such as attention-deficit and hyperactivity disorder (ADHD) and autism spectrum disorder (ASD). This study based on review of literature, the association of etiologically diagnosed childhood epilepsy with the subsequent risks of neurodevelopmental disorders. Papers for this review were selected from established databases like PubMed, Proquest, and ScienceDirect among many. It has shown high comorbidity between epilepsy and intellectual deficits. However, it merely hints at common neurological mechanisms and does not adequately imply causation. Medications for treating epilepsy in children are also implicated in the development of neurodevelopmental disorders later in life. These claims are also explored in the review. There may be common mechanisms between epilepsy and neurodevelopmental disorders, which has to be further explored to develop causal factors. There is not much literature on the neurodevelopmental effects of antiepileptic drugs in the postnatal phase.
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