Comparison of mydriatic effect and irritative symptoms between mydriatic drug-soaked sponge packing and conventional instillation

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Nattapol Wongkumchang Irada Sirikridsada

Abstract

Objective: To evaluate the pupil diameter and irritative symptom by the using of mydriatic drug-soaked sponge packing versus conventional instillation technique in the patients who need fundus examination.
Methods: With 40 patients, were dilated pupils by applying mydriatic drug-soaked sponge in one eye and using conventional technique in another eye. The soaked sponge were packed for 20 mins, pupils’diameter was checked every 10 mins for 3 times, and recorded irritative symptom in 30 mins.
Results: The mean pupil diameter after mydriatic drugs applying at 10, 20 and 30 minutes were 3.2 ± 1.0, 5.5 ± 1.3 and 7.0 ± 1.1 mm. by drug soaked sponge technique versus 3.2 ± 0.8, 5.4 ± 1.1 and 6.5 ± 1.0 mm by conventional technique respectively (p=0.661, 0.682, 0.974). The irritative symptom score was 4.9 ± 2.6 in mydriatic drug soaked sponge group and 3.0 ± 2.4 in conventional group (p=0.0006).
Conclusion: The mydriatic drug soaked sponge technique can provide a similar mydriatic effect to the conventional instillation technique. The sponge technique uses less number of staff and their effort. However this technique can cause significant irritation or foreign body sensation in some patients.
Conflicts of interest: The authors report no conflicts of interest.

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Original Study

References

1.Catherine TR, Francis JM. Medication-Soaked Pledgets to Dilate Pupils for Cataract Surgery. Journal of LGH.
2008;3:65-9.
2.Bartlett J, Jaanus SD. 5th Clinical Ocular Pharmacology. Burlington: Elsevier Science; 2013.
3.Davies P. 2ndThe Actions and Uses of 62 Eye South East Asia Vol. 14 Issue 1 2019 Ophthalmic Drugs. London: Butterworth; 2013.
4.Garg A, Pandey S. 3rd Text book of Ocular therapeutics. New Delhi: Jaypee Brothers Medical Publishers; 2013.
5.Thanathanee O, Ratanapakorn T, Morley MG, Yospaiboon Y. Lower conjunctivalfornix packing for mydriasis in premature infants: a randomized trial. ClinOphthalmol. 2012;6:253-6.
6.Dubois V, Wittles N, Lamont M, Madge S, Luck J. Randomised controlled single-blind study of conventional versus
depot mydriatic drug delivery prior to cataract surgery. BMC Ophthalmology 2006;6(1):36
7.McCormick A, Srinivasan S, Harun S, Watts M. Pupil dilation using a pledget sponge: a randomized controlled trial.
Clinical & Experimental Ophthalmology 2006;34(6):545-9.
8.Trinavarat A, Pituksung A. Effective pupil dilatation with a mixture of 0.75% tropicamide and 2.5% phenylephrine: A
randomized controlled trial. Indian Journal of Ophthalmology. 2009;57(5):351.