Journal of Health Science and Medical Research <div class="container-fluid"> <div class="row"> <div class="col-sm-3"><img src="/public/site/images/somjot/Cover-JHSMR-v2.jpg"></div> <div class="col-sm-9">&nbsp; <table> <tbody> <tr> <td style="width: 20px;">&nbsp;</td> <td> <p>Journal of Health Science and Medical Research is an online, quarterly peer reviewed scientific journal published by Prince of Songkla University. This journal aims to publish original article, review article, case reports in all aspects of basic and applied medical and health sciences. Manuscripts submitted to Journal of Health Science and Medical Research will be accepted on the understanding that the author must not have previously submitted the paper to another journal or have published the material elsewhere. The journal does not charge for submission, processing or publication of manuscripts and even for color reproduction of photographs.</p> <p><strong>Frequency: </strong>4 issues per year (Jan-Mar, Apr-Jun, Jul-Sep and Oct-Dec)</p> </td> </tr> </tbody> </table> </div> </div> </div> Journal of Health Science and Medical Research, Faculty of Medicine, Prince of Songkla University, Thailand en-US Journal of Health Science and Medical Research 2586-9981 Prevalence of Noise-Induced Hearing Loss in Workers with Noise Exposure in Panyananthaphikkhu Chonprathan Medical Center, Srinakharinwirot University <p><strong>Objective:</strong> To determine the prevalence of noise-induced hearing loss (NIHL) in workers in Panyananthaphikkhu Chonprathan Medical Center, Srinakharinwirot University (PCMC). The risk factors associated with noise-induced hearing loss were evaluated.<br><strong>Material and Methods:</strong> A cross-sectional study was conducted to analyze the data of 82 patients (43 males and<br>39 females) between June 2018 and July 2018. Subjects were between 20 and 59 years of age. All of them worked in loud environments in PCMC, using extended high-frequency audiometry (EHFA). The results of hearing loss in the group of EHFA and conventional audiometry were compared using the chi-squared test, McNemar’s chi-squared test and Fisher’s exact test. Multivariate logistic regression analysis was used for evaluating the risk factors.<br><strong>Results:</strong> The prevalence of NIHL was 41.5%. The risk factors associated with NIHL were smoking [odds ratio (OR)=5.6, p-value=0.002 (95% confidence interval (CI)=1.66-18.86)] and age over 40 years [OR=10.38, p-value&lt;0.001 (95% CI=2.82-38.24)].<br><strong>Conclusion:</strong> Epidemic NIHL continues to increase in the workplace, particularly in individuals with an age of over 40 years who smoke. Early detection of this irreversible disorder of the inner ear should be attempted.</p> <p>&nbsp;</p> Kotchporn Wongsuwan Kotchakarn Rattanaarun Katsarin Kittiwannawong ##submission.copyrightStatement## 2019-02-13 2019-02-13 81 92 10.31584/jhsmr.201941 Incidence of hypotension between Intrathecal Hyperbaric Bupivacaine with and without Fentanyl in Geriatric Patients Undergoing Urological Surgeries <p><strong>Objective:</strong> We aimed to assess the efficacy, the incidence of hypotension and adverse consequences of using intrathecal hyperbaric bupivacaine in comparison to a combination of low dose hyperbaric bupivacaine and fentanyl, in geriatric patients undergoing urological surgeries.<br><strong>Material and Methods:</strong> Our study was a prospective, triple-blinded and randomized controlled. One hundred and fortyeight geriatric participants scheduled for urological surgeries were randomly assigned into two groups: Group B (n=74) received intrathecal injection with 0.5% hyperbaric bupivacaine 1.5 milliliters (ml) alone (7.5 milligrams; mg), while Group F (n=74) received 0.5% hyperbaric bupivacaine 1 ml (5 mg) plus 0.5 ml of fentanyl (25 micrograms; mcg) making up to a total volume of 1.5 ml.<br><strong>Results:</strong> One hundred and forty-eight patients were included however, six patients were excluded from statistical analysis, due to an inadequate level of anesthesia; hence, 142 patients were analyzed. The incidence of hypotension in group B was: 9.7%, and in group F the percentage was 12.9%, respectively (p-value=0.74). There was no significant difference in regards to the highest sensory level in both groups. The anesthesia level in group B was Thoracic level 11 (T10-T12), and in group F it was 11 (T10-T12) (p-value=0.68), while the analgesia level in group B was Thoracic level 7 (T6-T8) with group F being a Thoracic level 6 (T6-T8) (p-value=0.16). The occurrence of bradycardia, and respiratory depression did not differ between the 2 groups.<br><strong>Conclusion:</strong> Intrathecal administration of 5 mg of 0.5% hyperbaric bupivacaine, plus 25 mcg of fentanyl provided an adequate level of sensory blockade, but did not decrease the frequency of hypotension.</p> Thavat Chanchayanon Mareeya Chearong Piyaporn Vasinanukorn Natsana Withayanuphakorn Tidarat Sangkaew ##submission.copyrightStatement## 2019-03-14 2019-03-14 93 99 10.31584/jhsmr.201944 Effects of Trehalose and Sucrose on Human Sperm Motility, Vitality and Morphology after Cryopreservation <p><strong>Objective:</strong> To compare human sperm motility, vitality and morphology after cryopreservation among sucrose, and different trehalose concentrations.<br><strong>Material and Methods:</strong> A total number of 124 normozoospermic semen samples were collected. Each semen sample was divided into 4 portions, and cryopreserved in a human sperm-preserving medium along with cryoprotectants, including; 50 milimolar (mM) trehalose, 100 mM trehalose, 200 mM trehalose and 50 mM sucrose, respectively. All semen samples were frozen by using a vapor phase method. Post-thawed sperm motility, vitality and morphology were assessed. R program was used for data analysis. A p-value of &lt;0.05 was considered statistically significant.<br><strong>Results:</strong> Post-thawed semen evaluation indicated that 50 mM trehalose was better than 50 mM sucrose in all sperm parameters, which included progressive motility (p-value=0.037, total motility (p-value&lt;0.001), vitality (p-value&lt;0.001) and morphology (p-value&lt;0.001). The sperm parameters were not significantly different among 100 mM trehalose, 200 mM trehalose and 50 mM sucrose.<br><strong>Conclusion:</strong> The use of 50 mM trehalose, as non-permeating cryoprotectant, showed superior post-thaw sperm<br>parameters over sucrose, and other trehalose concentrations.</p> Manaphat Suksai Kriengsak Dhanaworavibul ##submission.copyrightStatement## 2019-03-18 2019-03-18 101 107 10.31584/jhsmr.201945 The Effect of Quail Egg and Hen Egg Consumption on Low-Density Lipoprotein Oxidation and Small Dense Low-Density Lipoprotein <p><strong>Objective:</strong> The aim of the study was to investigate the effect of quail egg and hen egg supplements on lipoprotein profiles, low-density lipoprotein (LDL) oxidation and small dense LDL cholesterol (sd-LDL-C) in young healthy people, compared with hen eggs.<br><strong>Material and Methods:</strong> Twenty-three healthy volunteers (11 men and 12 women) were randomly assigned to consume 3 whole hen eggs per day (hen group, n=11) (total cholesterol 633 mg) or 9 quail eggs per day (quail group, n=12) (total cholesterol 459 mg) for 30 days. The plasma cholesterol and plasma triglyceride concentrations and lipoprotein fractions (Triglyceride-rich lipoprotein; TRL, LDL and high-density lipoprotein; HDL) were determined at baseline and after the 30-day period of egg consumption. The LDL oxidation (lag time) was measured by the increase of conjugated diene production. Sd-LDL-C was calculated from the major lipid and lipoprotein parameters.<br><strong>Results:</strong> In the quail group, plasma triglyceride (TG) and LDL-TG were significantly decreased, whereas the plasma cholesterol and HDL-C were unchanged. There was no alteration in lipoprotein profiles in the hen group. The LDL lag time of the quail group was longer than at baseline. There were no significant changes in sd-LDL-C levels in both groups during the study.<br><strong>Conclusion:</strong> Quail egg and hen egg consumptions for 30 days did not change the lipoprotein profiles, sd-LDL as well as the LDL-oxidation, which not modified the cardiovascular disease risk factor.</p> Raveenan Mingpakanee Chatchanok Chaisitthichai Nattaporn Wichitamporn Paradee Sappittayakorn Suparnnikar Phongphanwatana ##submission.copyrightStatement## 2019-03-28 2019-03-28 109 120 10.31584/jhsmr.201946 Prevalence of Atypical Disorders and Associated Factors in Undergraduate Students of Prince of Songkla University, Songkhla, Thailand <p><strong>Objective:</strong> To quantify the prevalence of eating disorders and factors associated with eating disorders among undergraduate students in Prince of Songkla University, Hat Yai Campus.<br><strong>Material and Methods:</strong> This study was a cross sectional descriptive study using random sampling by proportionate accidental sampling. We used the Thai Eating Attitudes Test-26 (EAT-26) for collecting information about eating attitudes. Participants who had scores equal or higher than 12 (≥12) were assumed to have atypical eating attitudes and behaviors. We used the R and R studio program to analyze information. Multivariate logistic regression was used for correlation analysis.<br><strong>Results:</strong> In this study, we had completed questionnaires from 500 students (response rate 65.6%). The overall prevalence of atypical eating attitudes and behaviors in undergraduate students in Prince of Songkla University, Hat Yai Campus was 37.2%. We found that overweight body mass index (BMI) (BMI 23.00-24.99 kg/m2) and obesity BMI (≥25.00 kg/m2) were significantly more prevalent in students with atypical eating attitudes and behaviors than normal BMI (18.50-22.99 kg/m2), with odds ratios of 3.3 [95% confidence interval (CI)=1.8-6.2] and 3.7 (95% CI=1.9-6.9), respectively. However, multivariate logistic regression revealed no associations between atypical eating attitudes and behaviors, sex, target weight, biological disease, psychological disease, current medication(s) or faculty. Atypical eating attitudes and behaviors were significantly associated only with body mass index BMI. The overweight and obese BMI groups had significantly increased risks of 3.3 and 3.7 times of atypical eating attitudes and behaviors compared to the normal group, with 95% CIs of 1.8-6.2 and 1.9-6.9, respectively.<br><strong>Conclusion:</strong> From this study, overweight BMI and obesity BMI were significantly more prevalent in students with atypical eating attitudes and behaviors than normal BMI. BMI was the only factor significantly associated with atypical eating attitudes and behaviors.</p> Orapan Fumaneeshoat ##submission.copyrightStatement## 2019-04-11 2019-04-11 121 131 10.31584/jhsmr.201947 Outcomes of Speech and Language Abilities and Quality of Life in Thai People with Aphasia by Group Therapy <p><strong>Objective:</strong> The purpose of this study was to compare before- and after-scores of speech and language abilities, and quality of life of Thai people with aphasia.<br><strong>Material and Methods:</strong> A cross-sectional study was conducted at the Speech Clinic in Ramathibodi Hospital from July 2016 to March 2017. Participants were 11 Thai people with aphasia. They received group therapy for three hours per session, for eight sessions, within three to five months. The measurement of speech and language abilities was assessed using the Thai Adaptation of the Western Aphasia Battery (WAB). The measurement of quality of life was assessed using the Thai version of the Stroke Impact Scale (SIS) 3.0. The results were analyzed using descriptive statistics and a paired samples t-test for comparisons of the mean scores before and after group therapy.<br><strong>Results:</strong> Of the participants, there were 8 males (72.8%) and 3 females (27.3%) with aphasia. They ranged in age from 27 to 68, with a mean age of 48.55±13.42 years. Results showed that the differences in the improvements of speech and language abilities scores and quality of life scores of these participants after group therapy were significant and higher than their scores before group therapy (p-value&lt;0.01).<br><strong>Conclusion:</strong> Group therapy may be an efficient and effective way to rehabilitate the speech and language abilities and quality of life of Thai people with aphasia.</p> <p>&nbsp;</p> Tidajun Jiaranai Jeamjai Jeeraumporn Sumalee Dechongkit Montip Tiensuwan ##submission.copyrightStatement## 2019-04-30 2019-04-30 133 144 10.31584/jhsmr.201948 Comparison of efficacy between bamboo and stainless steel finger trap: An experimental study <p><strong>Objective:</strong> The Chinese finger trap is a device used to aid in reduction of fractures, especially in distal end of radius fractures. The stainless steel finger trap is widely used but often causes fingers pain. We adapted a bamboo finger trap to reduce pain and also provide a lower cost alternative.<br><strong>Material and Methods:</strong> This was a cross-over study in healthy volunteers comparing bamboo and stainless-steel finger traps. Each participant underwent two tests, one with the stainless steel finger trap and another with the bamboo finger trap. For each trial, the participant lay supine on a bed, and the finger trap was attached to the index and middle fingers of the participant, with the arm suspended by a metal loop at the top of the trap to the elbow level of the patient on the bed. Weights were incrementally added to a weight bag suspended by a strap over the patient’s upper arm at one pound per minute until a maximum weight of 20 lbs. and the participant was asked to rate the degree of discomfort with the increasing weights using a visual analogue score (VAS)<br><strong>Results:</strong> Thirty volunteers were tested, all of whom were tested with both the bamboo and stainless steel traction devices. One patient developed a superficial skin injury while the stainless steel device was being applied. Overall, the bamboo finger trap group had lower VAS scores than the stainless steel group in the first fifteen minutes (p-value&lt;0.001).<br><strong>Conclusion:</strong> The bamboo finger trap is an effective alternative to the stainless steel finger trap, causing less pain.</p> Thanachai Thongtanworapat Porames Suwanno Sittichoke Anuntaseree ##submission.copyrightStatement## 2019-05-03 2019-05-03 145 150 10.31584/jhsmr.201949 Elephantiasic Pretibial Myxedema: A Rare Manifestation in Graves’ Disease <p>Elephantiasic pretibial myxedema is an extremely rare condition, affecting patients with thyroid disease. The<br>clinical manifestation is difficult to diagnosis, and the treatment is challenging. Herein, the authors report on a case of a patient with Graves’ disease, who had a long-standing enlargement of bilateral legs, and histopathologic studies confirmed the diagnosis as; pretibial myxedema. The patient was treated with an antithyroid drug, iodine-131 (131I) irradiation, a potent topical corticosteroid, with occlusion, and compression therapy, however, the patient’s skin condition remained unchanged. This report aims to demonstrate a rare form of pretibial myxedema, to review the clinical presentations, differential diagnosis as well as therapeutic options.</p> Apichat Kaewdech Kumpol Aiempanakit Siripan Sangmala Kanokphorn Chiratikarnwong Sauvarat Auepemkiate Josef Symon S. Concha ##submission.copyrightStatement## 2019-02-28 2019-02-28 151 155 10.31584/jhsmr.201942 Regulation and Decriminalisation of Illegal Substances in Thailand <p>Psychoactive substances – chemical compounds which can alter a person’s mood, thoughts, and behaviors may be liable to misuse and cause addiction. Internationally, many strategies have been implemented in order to limit the supply and demand of illegal substances, with a wide variation at the country level. Thailand is an upper-middle income country in Southeast Asia. Since 2015, Thai authorities and policymakers have instituted many changes to the legal controls on illegal drugs. The aim of this review was to summarise the history of drug control and regulation in Thailand, focusing on opioids (including Kratom), methamphetamines and cannabis, and the outcome of recent strategies. Recent measures towards decriminalising substance use disorders are also discussed.</p> Rasmon Kalayasiri Teerayuth Rungnirundorn Robert Ali John Marsden ##submission.copyrightStatement## 2019-03-04 2019-03-04 157 162 10.31584/jhsmr.201943