The effect of cold compression as the pain and bleeding in the area of Botulinum Toxin typeA injection for hemifacialspasm patients

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Pajeepat Anurajsaena


Background: A 5-minutes cold compress can reduce pain during and after injection of Botulinum toxin type A, but the cold compress around the eye ball–where skin is very sensitive will cause a pain from the cold. The reduction of cold compress duration to  1-minute is reported to ease this pain and comfort the patients.

Objective: To study the duration effect of cold compresses on pain relief and reduction of bleeding at the injection area of botulinum toxin type A for hemifacialspasm  patients.

Materials and methods: A double-blind, randomized controlled study of 28 hemifacialspasm patients with  administrated at the spastic clinic Buddhasothorn Hospital. The 28 patients were randomly divided into 2 groups : the experimental group received a  1-minute cold compress prior to the botulinum toxin type A injection and secondly the control group received a 5-minutes cold compress before the injection.

Results: The  experimental group and the control group had the pain score 3.3±1.5 and 2.8±1.8. Bleeding at the injection site was 14.3% and 7.1% which was no statistical differences (p = 0.43, p = 1)

Conclusions: A 1-minute and 5-minutes cold compress prior of Botulinum toxin type A  injection for hemifacialspasm patients had not statistical differences in decreasing pain (NRS)  and  bleeding at injection site.


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นิพนธ์ต้นฉบับ (Original article)


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