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The objective of this study was to determine 1)antiretroviral (ARV) medicationadherence and factorsassociatedwith controllingCD4 level and 2)incidence of adverse drug reaction(ADR). This cross-sectional descriptive study collected important variablesfrom HOSxP, NAP plus database, Medical recordswere reviewed. Sample were305 HIV-infected patients with ICD 10 code B20-24 who attending HIV/AIDs outpatientclinic atSungkha Hospital, Surin province.The average age and duration of antiretroviral (ARV) use of participants were 41.16±9.03 years, average duration of ARV medication use were 69.84±34.68 months, respectively. The rate of non-adherence measured by pill counts was 12.8% (taking less than 95% of prescribed doses). Risk factors for controllable of CD4were female (Odds ratio (OR) = 0.44; 95%CI: 0.26-0.72), ARV use for more than 60 months(OR=0.39, 95%CI: 0.23-0.65)and missing an appointment (OR=0.31, 95%CI: 0.14-0.67). The most of detected ADR of ARV medication was severe nausea vomiting. This study indicated many associated factors affected CD4 level control. The monitoring patients with theseassociated factors arecontinuouslyneeded.
adherence, antiretroviral, factor