Synthesis, Characterization and In vitro Antibacterial Evaluation of Oxadiazole Derivatives

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Kiran Metha

Abstract

This research paper reports novel oxadiazole derivatives. Such compounds were prepared and their complexation was performed by treating them with metal salts of Mn(II), Co(II) and Ni(II). The synthesized derivatives were characterized by elemental analysis, IR and electronic spectral studies and magnetic moment studies. Their structures were further supported by 1H NMR spectra. The magnetic behaviour and spectroscopic investigation of complexes indicates mononuclear octahedral structure for complexes. All the derivatives were screened for antibacterial activity against Pseudomonas aeruginosa, Staphylococcus aureus, Bacillus subtilis, Klebsiella pneumonia andEscherichia coli. It showed noticeable antibacterial activity. 

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How to Cite
Metha, K. (2017). Synthesis, Characterization and In vitro Antibacterial Evaluation of Oxadiazole Derivatives. Science, Engineering and Health Studies, 11(1), 27–35. https://doi.org/10.14456/sustj.2017.3
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Research Articles

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