Prevalence and Associated Factors of Positive Margins of Cervical Tissue from Loop Electrosurgical Excision Procedure

Main Article Content

Rawisara Champawong
Saowanee Tangmanowuthikul
Surapong Saenpoch
Srisuda Songthamwat
Metha Songthamwat

Abstract

Objective: Primary objective is to study the prevalence of positive margins of cervical tissue from loop electrosurgical excision procedure (LEEP) for conization and secondary objective is to determine its associated factors.


Materials and Methodss: Medical records of 350 patients who underwent LEEP in Udonthani Hospital form March 2016 to July 2018 were reviewed. Data collection included baseline characteristics, preoperative cytology, colposcopic finding, colposcopic directed biopsy histology, histopathological diagnosis, margin of surgical specimens and all related histologic results. The prevalence and associated factors for positive margins were analyzed.


Results: There were 323 patients who underwent LEEP and had complete data. The mean age was 42.3+10.6 years. The majority of them had a body mass index < 30 kg/m2 (94.1%), multiparous (88.8%), negative test of human immunodeficiency virus antibody (91.3%) and premenopausal status (76.2%). The prevalence of positive margins of cervical tissue form LEEP was found in 80 cases (24.8%), and the most positive margin site was endocervix (48.8%). From multivariate logistic regression analysis, colposcopic directed biopsy histology > cervical intraepithelial neoplasia 2 was the only significant factor associated with the positive margins; adjusted odds ratio 3.91, 95% confidence interval 1.35-11.27.


Conclusion: The prevalence of positive margins of cervical tissue from LEEP was almost one-fourth. The high grade of the colposcopic directed biopsy histology was a significant factor associated with having positive margins.

Article Details

How to Cite
(1)
Champawong, R.; Tangmanowuthikul, S.; Saenpoch, S.; Songthamwat, S.; Songthamwat, M. Prevalence and Associated Factors of Positive Margins of Cervical Tissue from Loop Electrosurgical Excision Procedure. Thai J Obstet Gynaecol 2019, 27, 187-194.
Section
Original Article
Author Biographies

Saowanee Tangmanowuthikul, Department of Obstetrics and Gynecology, Udonthani Hospital, Udonthani, Thailand

Department of Obstetrics and Gynecology, Udonthani Hospital, Udonthani, Thailand, 41000

Metha Songthamwat, Department of Obstetrics and Gynecology, Udonthani Hospital, Udonthani, Thailand

Department of Obstetrics and Gynecology, Udonthani Hospital, Udonthani, Thailand, 41000

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