Small dosages of alpha1 adrenoceptor antagonist on goat semen quality and seminal fluid volume

Abstract

The frozen goat semen process must wash seminal fluid from goat semen. A small dosage of alpha1
adrenoceptor antagonist or tamsulosin may reduce seminal fluid in goat. A latin square 4x4 was applied to twelve male
goats to receive either normal saline (NSS), tamsulosin 3, 6 and 9 g/kg intramuscular injection at one-week intervals.
Semen collection by artificial vagina and libido scoring was performed within one-hour post injection. Semen quality
and seminal fluid were evaluated after semen collection The results showed that none of the libido scores in the groups
was different. Anejaculations occurred in 1 (8.3%), 3 (25%) and 4 (33.3%) using tamsulosin 3, 6 and 9 g/kg,
respectively. Only, the volume of seminal fluid in tamsulosin 9 g/kg has significantly lower than the NSS group.
Other semen quality did not show any significant difference. Although, in this experiment, the alpha1 adrenoceptor
antagonist or tamsulosin could reduce the amount of seminal fluid in goats anejaculation was promoted in all dosages
of tamsulosin one hour after injection. Therefore, this drug may not suitable in reducing seminal fluid when producing
goat frozen semen.