The Effect of Mobile Application on Medication Adherence in Patients with Acute Coronary Syndrome after Hospitalization
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Published:
Apr 30, 2018
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Abstract
This RCT study aimed to examine the effects of mobile application on medication adherence in patients with acute coronary syndrome after hospitalization. Participants were randomly assigned using block random assignment into an experimental (n=28) and control group (n=28). Both groups received an ACS medication handbook and the usual care treatment. In addition, the experimental group was given a mobile application featuring a reminder, medication information, medication taken recording system, and connecting data system with the researcher. There was a 4-week trial period for the patients to become accustomed to the application. Data were analyzed non-parametrically using the
Mann-Whitney U Test.
The results of this study revealed that the experimental group had medication adherence scores higher than the control group by 78.5%. The difference was statistically significant (p<.01).
The adherence scores of the control group improved by 32.15%.
As a result, the mobile application was recommended as a major improvement to medication
adherence of patients with ACS after hospitalization. Consequently, their rate of re-admission to
hospital and disease progression would be significantly reduced. Thus, mobile application should be
used and continuously developed for more functions and more adaptability to each patient’s
treatment plan and lifestyle.
Article Details
How to Cite
1.
สีเสน่ห์ ส, วัฒนกิจไกรเลิศ ด, เจริญกิจการ ว, ทุมวิภาต ฉ, วานิชชา ว. The Effect of Mobile Application on Medication Adherence in Patients with Acute Coronary Syndrome after Hospitalization. NJPH (วารสาร พ.ส.) [Internet]. 2018 Apr. 30 [cited 2024 Apr. 18];28(1):61-74. Available from: https://he02.tci-thaijo.org/index.php/tnaph/article/view/121244
Section
บทความวิจัย
บทความและรายงานวิจัยในวารสารพยาบาลกระทรวงสาธารณสุข เป็นความคิดเห็นของ ผู้เขียน มิใช่ของคณะผู้จัดทำ และมิใช่ความรับผิดชอบของสมาคมศิษย์เก่าพยาบาลกระทรวงสาธารณสุข ซึ่งสามารถนำไปอ้างอิงได้
References
1. Libby P, Theroux P. Pathophysiology of coronaryartery disease. Circulation. 2005;111(25):
3481-8.
2. Srimahachota S, Boonyaratavej S, Kanjanavanit R, Sritara P, Krittayaphong R, Kunjara Na-Ayudhya R, et al. Thai Registry in Acute Coronary Syndrome (TRACS)-an extension of Thai Acute Coronary Syndrome Registry (TACS) group: lower in-hospital but still high mortality at one-year. Journal of the Medical Association of Thailand. 2012;95(4):508.
3. Vanasse A, Courteau J, Niyonsenga T. Revascularization and cardioprotective drug treatment in myocardial infarction patients: how do they impact on patients’ survival when delivered as usual care. BMC cardiovascular disorders. 2006;6:21.
4. Spertus JA, Kettelkamp R, Vance C, Decker C, Jones PG, Rumsfeld JS, et al. Prevalence, predictors, and outcomes of premature discontinuation of Thienopyridine therapy after drug-eluting stent placement. Results from the PREMIER Registry. 2006;113(24):2803-9.
5. Molloy GJ, Messerli-Burgy N, Hutton G, Wikman A, Perkins-Porras L, Steptoe A. Intentional and unintentional non-adherence to medications following an acute coronary syndrome: A longitudinal study. J Psychosom
Res. 2014;76(5):430-2.
6. Kronish IM, Ye S. Adherence to cardiovascular medications: lessons learned and future directions.
Progress in Cardiovascular Diseases. 2013;55(6):590-600.
7. Stegemann S, Baeyens J-P, Cerreta F, Chanie E, Löfgren A, Maio M, et al. Adherence measurement systems and technology for medications in older patient populations. European Geriatric Medicine. 2012;3(4):254-60.
8. Sadoyoo S, Jirapreeya N, Treesak C, Sangjam P. Leftover medications in patients with chronic diseases from home health care visits: a community study in Bangkok. Dialogue on Pharmacy and Health Care Practice. 2014;1(1):1-7.(in Thai).
9. Kripalani S, Yao X, Haynes RB. Interventions to enhance medication adherence in chronic medical conditions: a systematic review. Archives of Internal Medicine. 2007;167(6):540-9.
10. Lee JK, Grace KA, Taylor AJ. Effect of a pharmacy care program on medication adherence and persistence, blood pressure, and low density lipoprotein cholesterol: a randomized controlled trial. JAMA. 2006;296(21):2563-
71.
11. Kripalani S, Schmotzer B, Jacobson TA. Improving Medication Adherence through Graphically Enhanced Interventions in Coronary Heart Disease (IMAGE-CHD): a randomized
controlled trial. Journal of General Internal Medicine. 2012;27(12):1609-17.
12. Murray MD, Young J, Hoke S, Tu W, Weiner M, Morrow D, et al. Pharmacist intervention to
improve medication adherence in heart failure: a randomized trial. Annals of Internal Medicine. 2007;146(10):714-25.
13. Chapman B, Bogle V. Adherence to medication and self-management in stroke patients. British Journal of Nursing. 2014;23(3):158-66.
14. Bailey SC, Belter LT, Pandit AU, Carpenter DM, Carlos E, Wolf MS. The availability, functionality, and quality of mobile applications supporting medication self-management. Journal of the American Medical Informatics Association. 2013;21(3):542-6.
15. Dayer L, Heldenbrand S, Anderson P, Gubbins PO, Martin BC. Smartphone medication adherence apps: potential benefits to patients and providers. Journal of the American Pharmacists Association: JAPhA. 2013;53(2):172.
16. De Jongh T, Gurol-Urganci I, Vodopivec Jamsek V, Car J, Atun R. Mobile phone messaging for facilitating self-management of long-term illnesses. The Cochrane Library. 2012.
17. Fisher JD, Fisher WA, Amico KR, Harman JJ. An information-motivation-behavioral skills model of adherence to antiretroviral therapy. Health Psychol. 2006;25(4):462-73.
18. Griffiths J, Puttinoi S, Pongsaksri M. The General Practitioner Assessment of Cognition; GP-COG (Thai Version): validity and reliability. 2012. (in Thai)
19. Horne R, Weinman J, Barber N, Elliott R, Morgan M, Cribb A. Concordance, adherence and compliance in medicine taking. London: NCCSDO. 2005:40-6.
20. Homvisetvongsa S, Pinyopasakul W, Chareonkitkarn V. The Influence of attitude, subjective norm, perceived behavior control on medication adherence in patients with coronary artery disease. Journal of Nursing Science
Chulalongkorn University [Internet]. 1 [cited 17Mar.2018];27(3):119-2. Available from: https://www.tci-thaijo.org/index.php/CUNS/article/view/76688. (in Thai)
21. Kripalani S, Schmotzer B, Jacobson TA. Improving medication adherence through graphically enhanced interventions in coronary heart disease (IMAGE-CHD): a randomized controlled trial. Journal of general internal medicine. 2012;27(12):1609-17.
22. Perera AI, Thomas MG, Moore JO, Faasse K, Petrie KJ. Effect of a smartphone application incorporating personalized health-related imagery on adherence to antiretroviral therapy: a randomized clinical trial. AIDS patient care
and STDs. 2014;28(11):579-86.
23. Santo K, Richtering SS, Chalmers J, Thiagalingam A, Chow CK, Redfern J. Mobile phone apps to improve medication adherence: a systematic stepwise process to identify high quality apps. JMIR mHealth and uHealth.
2016;4(4).
24. Dayer L, Heldenbrand S, Anderson P, Gubbins PO, Martin BC. Smartphone medication adherence apps: potential benefits to patients and providers. Journal of the American Pharmacists Association. 2013;53(2):172-81.
25. Patel S, Jacobus-Kantor L, Marshall L, Ritchie C, Kaplinski M, Khurana PS, et al. Mobilizing your medications: an automated medication reminder application for mobile phones and hypertension medication adherence in a high-risk urban population. SAGE Publications; 2013.
26. Mira JJ, Navarro I, Botella F, Borrás F, Nuño-Solinís R, Orozco D, et al. A Spanish pillbox app for elderly patients taking multiple medications: randomized controlled trial. Journal of Medical Internet Research. 2014;16(4).
27. Athilingam P, Labrador MA, Remo EFJ, Mack L, San Juan AB, Elliott AF. Features and usability assessment of a patient-centered mobile application (HeartMapp) for self-management of heart failure. Applied Nursing Research. 2016;32:156-63.
28. Jintana P, Sriyuktasuth A, Pongthavornkamol K, Nata N. Information-Motivation-Behavioral Skills Program improved phosphate binder adherence in patients with chronic hemodialysis. J Nurs Sci. 2016;34(2):92-101. (in Thai)
3481-8.
2. Srimahachota S, Boonyaratavej S, Kanjanavanit R, Sritara P, Krittayaphong R, Kunjara Na-Ayudhya R, et al. Thai Registry in Acute Coronary Syndrome (TRACS)-an extension of Thai Acute Coronary Syndrome Registry (TACS) group: lower in-hospital but still high mortality at one-year. Journal of the Medical Association of Thailand. 2012;95(4):508.
3. Vanasse A, Courteau J, Niyonsenga T. Revascularization and cardioprotective drug treatment in myocardial infarction patients: how do they impact on patients’ survival when delivered as usual care. BMC cardiovascular disorders. 2006;6:21.
4. Spertus JA, Kettelkamp R, Vance C, Decker C, Jones PG, Rumsfeld JS, et al. Prevalence, predictors, and outcomes of premature discontinuation of Thienopyridine therapy after drug-eluting stent placement. Results from the PREMIER Registry. 2006;113(24):2803-9.
5. Molloy GJ, Messerli-Burgy N, Hutton G, Wikman A, Perkins-Porras L, Steptoe A. Intentional and unintentional non-adherence to medications following an acute coronary syndrome: A longitudinal study. J Psychosom
Res. 2014;76(5):430-2.
6. Kronish IM, Ye S. Adherence to cardiovascular medications: lessons learned and future directions.
Progress in Cardiovascular Diseases. 2013;55(6):590-600.
7. Stegemann S, Baeyens J-P, Cerreta F, Chanie E, Löfgren A, Maio M, et al. Adherence measurement systems and technology for medications in older patient populations. European Geriatric Medicine. 2012;3(4):254-60.
8. Sadoyoo S, Jirapreeya N, Treesak C, Sangjam P. Leftover medications in patients with chronic diseases from home health care visits: a community study in Bangkok. Dialogue on Pharmacy and Health Care Practice. 2014;1(1):1-7.(in Thai).
9. Kripalani S, Yao X, Haynes RB. Interventions to enhance medication adherence in chronic medical conditions: a systematic review. Archives of Internal Medicine. 2007;167(6):540-9.
10. Lee JK, Grace KA, Taylor AJ. Effect of a pharmacy care program on medication adherence and persistence, blood pressure, and low density lipoprotein cholesterol: a randomized controlled trial. JAMA. 2006;296(21):2563-
71.
11. Kripalani S, Schmotzer B, Jacobson TA. Improving Medication Adherence through Graphically Enhanced Interventions in Coronary Heart Disease (IMAGE-CHD): a randomized
controlled trial. Journal of General Internal Medicine. 2012;27(12):1609-17.
12. Murray MD, Young J, Hoke S, Tu W, Weiner M, Morrow D, et al. Pharmacist intervention to
improve medication adherence in heart failure: a randomized trial. Annals of Internal Medicine. 2007;146(10):714-25.
13. Chapman B, Bogle V. Adherence to medication and self-management in stroke patients. British Journal of Nursing. 2014;23(3):158-66.
14. Bailey SC, Belter LT, Pandit AU, Carpenter DM, Carlos E, Wolf MS. The availability, functionality, and quality of mobile applications supporting medication self-management. Journal of the American Medical Informatics Association. 2013;21(3):542-6.
15. Dayer L, Heldenbrand S, Anderson P, Gubbins PO, Martin BC. Smartphone medication adherence apps: potential benefits to patients and providers. Journal of the American Pharmacists Association: JAPhA. 2013;53(2):172.
16. De Jongh T, Gurol-Urganci I, Vodopivec Jamsek V, Car J, Atun R. Mobile phone messaging for facilitating self-management of long-term illnesses. The Cochrane Library. 2012.
17. Fisher JD, Fisher WA, Amico KR, Harman JJ. An information-motivation-behavioral skills model of adherence to antiretroviral therapy. Health Psychol. 2006;25(4):462-73.
18. Griffiths J, Puttinoi S, Pongsaksri M. The General Practitioner Assessment of Cognition; GP-COG (Thai Version): validity and reliability. 2012. (in Thai)
19. Horne R, Weinman J, Barber N, Elliott R, Morgan M, Cribb A. Concordance, adherence and compliance in medicine taking. London: NCCSDO. 2005:40-6.
20. Homvisetvongsa S, Pinyopasakul W, Chareonkitkarn V. The Influence of attitude, subjective norm, perceived behavior control on medication adherence in patients with coronary artery disease. Journal of Nursing Science
Chulalongkorn University [Internet]. 1 [cited 17Mar.2018];27(3):119-2. Available from: https://www.tci-thaijo.org/index.php/CUNS/article/view/76688. (in Thai)
21. Kripalani S, Schmotzer B, Jacobson TA. Improving medication adherence through graphically enhanced interventions in coronary heart disease (IMAGE-CHD): a randomized controlled trial. Journal of general internal medicine. 2012;27(12):1609-17.
22. Perera AI, Thomas MG, Moore JO, Faasse K, Petrie KJ. Effect of a smartphone application incorporating personalized health-related imagery on adherence to antiretroviral therapy: a randomized clinical trial. AIDS patient care
and STDs. 2014;28(11):579-86.
23. Santo K, Richtering SS, Chalmers J, Thiagalingam A, Chow CK, Redfern J. Mobile phone apps to improve medication adherence: a systematic stepwise process to identify high quality apps. JMIR mHealth and uHealth.
2016;4(4).
24. Dayer L, Heldenbrand S, Anderson P, Gubbins PO, Martin BC. Smartphone medication adherence apps: potential benefits to patients and providers. Journal of the American Pharmacists Association. 2013;53(2):172-81.
25. Patel S, Jacobus-Kantor L, Marshall L, Ritchie C, Kaplinski M, Khurana PS, et al. Mobilizing your medications: an automated medication reminder application for mobile phones and hypertension medication adherence in a high-risk urban population. SAGE Publications; 2013.
26. Mira JJ, Navarro I, Botella F, Borrás F, Nuño-Solinís R, Orozco D, et al. A Spanish pillbox app for elderly patients taking multiple medications: randomized controlled trial. Journal of Medical Internet Research. 2014;16(4).
27. Athilingam P, Labrador MA, Remo EFJ, Mack L, San Juan AB, Elliott AF. Features and usability assessment of a patient-centered mobile application (HeartMapp) for self-management of heart failure. Applied Nursing Research. 2016;32:156-63.
28. Jintana P, Sriyuktasuth A, Pongthavornkamol K, Nata N. Information-Motivation-Behavioral Skills Program improved phosphate binder adherence in patients with chronic hemodialysis. J Nurs Sci. 2016;34(2):92-101. (in Thai)